Purvalanol B, MedChemExpress

Product Code.	Quantity	unitSize
16463517	50 mg	50mg
16459977	5 mg	5mg
16437498	10 mg	10mg

Product Code. 16463517 Supplier Medchem Express Supplier No. HY18299

Description

MedChemExpress Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum.

Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum.

Specifications

• Chemical Name or Material: Purvalanol B
• CAS: 212844-54-7
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₂₀H₂₅ClN₆O₃
• Quantity: 50 mg
• Synonym: NG 95
• Solubility Information: DMSO : ≥ 40 mg/mL (92.40 mM)
• SMILES: O=C(O)C1=CC=C(NC2=C3N=CN(C(C)C)C3=NC(N[C@@H](CO)C(C)C)=N2)C=C1Cl
• Molecular Weight (g/mol): 432.9
• Formula Weight: 432.9
• Percent Purity: 95.0%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only