Invitrogen™ PTPN21 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575804

Product Code. 15902335

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PTPN21 (protein tyrosine phosphatase, non-receptor type 21), also known as PTPD1 or PTPRL10, is a 1,174 amino acid member of the PTP family and localizes to both the cytoplasm and the cytoskeleton. Containing one FERM domain and one tyrosine-protein phosphatase domain, PTPN21 functions to catalyze the water-dependent conversion of a protein tyrosine phosphate into a protein tyrosine and a free phosphate and, via this catalytic activity, may be involved in liver regeneration and spermatogenesis. The gene encoding PTPN21 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.

Specifications

• Antigen: PTPN21
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPN21
• Gene Alias: dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21); protein tyrosine phosphatase 2E; protein tyrosine phosphatase, non-receptor type 21; protein-tyrosine phosphatase 2E; Protein-tyrosine phosphatase D1; protein-tyrosine phosphatase PTP-RL10; Ptp2E; PTPD1; Ptpn21; PTPRL10; Tyrosine-protein phosphatase non-receptor type 21
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11099, 171070, 24000
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16825, Q62136, Q62728
• Gene Symbols: PTPN21
• Immunogen: Synthetic peptide corresponding to residues in Human PTPN21.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG