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Invitrogen™ PTK7 Polyclonal Antibody
Description
A suggested positive control is human colon tissue lysate. PA5-20424 can be used with blocking peptide PEP-0541.
CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
Specifications
Specifications
| Antigen | PTK7 |
| Applications | Immunohistochemistry, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | Ptk7 |
| Gene Accession No. | Q13308, Q8BKG3 |
| Gene Alias | 8430404F20Rik; CCK4; CCK-4; chz; Colon carcinoma kinase 4; inactive tyrosine-protein kinase 7; mPTK7/CCK4; protein chuzhoi; protein tyrosine kinase 7; protein tyrosine kinase 7 (inactive); protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Ptk7; PTK7 protein tyrosine kinase 7; receptor tyrosine kinase-like protein; serum response factor; Srf; Tyrosine-protein kinase-like 7 |
| Gene Symbols | Ptk7 |
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