Invitrogen™ PTHLH Monoclonal Antibody (D1), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA550875

Product Code. 17950883

Description

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.

Specifications

• Antigen: PTHLH
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: P12272, P13085
• Gene Symbols: PTHLH
• Immunogen: Recombinant Rat PTHrP protein, Ala37-His177 (Accession #P13085).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Western Blot
• Clone: D1
• Conjugate: Unconjugated
• Gene: PTHLH
• Gene Alias: BDE2; calciotropic hormone, growth factor; HHM; osteostatin; parathyroid hormone like hormone; parathyroid hormone related peptide; parathyroid hormone-like hormone; parathyroid hormone-like hormone preproprotein; parathyroid hormone-like peptide; parathyroid hormone-like protein; parathyroid hormone-like related protein; parathyroid hormone-related peptide; parathyroid hormone-related protein; parathyroid-like peptide; PLP; PTHLH; PTH-like; PTHR; PTH-related peptide; PTH-related protein; Pthrp; PTH-rP; PTHrP[107-139]; PTHrP[1-36]; PTHrP[38-94]
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 24695, 5744
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid