Invitrogen™ PSMD12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA554701

Product Code. 15742631

Description

Immunogen sequence: WQQALKSVVL YVILAPFDNE QSDLVHRISG DKKLEEIPKY KDLLKLFTTM ELMRWSTLVE DYGMELRKGS LESPATDVFG STEEGEKRWK DLKNRVVEH Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation.

Specifications

• Antigen: PSMD12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMD12
• Gene Alias: 1500002F15Rik; 26S proteasome non-ATPase regulatory subunit 12; 26S proteasome non-ATPase regulatory subunit 1-like protein; 26S proteasome regulatory subunit p55; 26S proteasome regulatory subunit RPN5; AI480719; fc34f08; MGC75406; P55; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12; proteasome 26S non-ATPase subunit 12; proteasome 26S subunit non-ATPase 12; proteasome 26S subunit, non-ATPase 12; PSMD12; psmd12 protein; Rpn5; similar to proteasome 26S non-ATPase subunit 12 isoform 2; wu:fb38a06; wu:fc34f08; wu:fc49f02
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5718
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00232
• Gene Symbols: PSMD12
• Immunogen: Recombinant protein corresponding to Human PSMD12. Recombinant protein control fragment (Product #RP-93548).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG