Invitrogen™ PSMB3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA528999

Product Code. 13483117

Description

Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (91%), Dog (99%), Pig (97%), Rhesus Monkey (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Pseudogenes have been identified on chromosomes 2 and 12.

Specifications

• Antigen: PSMB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSMB3
• Gene Alias: AL033320; C10-II; HC10-II; MGC4147; proteasome (prosome, macropain) subunit, beta type 3; proteasome (prosome, macropain) subunit, beta type, 3; proteasome beta 3 subunit; proteasome chain 13; Proteasome component C10-II; proteasome subunit beta 3; proteasome subunit beta type-3; Proteasome theta chain; PSMB3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5691
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.96 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P49720
• Gene Symbols: PSMB3
• Immunogen: Full length human Proteasome 20S beta 3 Recombinant protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG