Invitrogen™ PSA Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595217

Product Code. 16354485

Description

Human PSA shares 54% amino acid (aa) sequence identity with rat PSA. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human LNCAP whole cell. IHC: human prostatic cancer tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.

Specifications

• Antigen: PSA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLK3
• Gene Alias: Antigen; antigen, prostate specific; APS; Fletcher factor; gamma-seminoprotein; hK3; Kal3; Kal-3; Kallikrein 3; kallikrein 3, plasma; kallikrein B, plasma 1; kallikrein related peptidase 3; kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; Kalp1; KALP15; Kininogenin; KLK2A1; Klk3; KLK-3; Klkb1; P-30 antigen; Pk; Plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; prostate specific antigen; prostate-specific (APS); prostate-specific antigen; PSA; Semenogelase; seminin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 354
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P07288
• Gene Symbols: KLK3
• Immunogen: E.coli-derived human PSA recombinant protein (Position: I25-P261).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG