Invitrogen™ PRX Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551646

Product Code. 15749600

Description

Immunogen sequence: MKVPDMKLPE IKLPKVPEMA VPDVHLPEVQ LPKVSEIRLP EMQVPKVPDV HLPKAPEVKL PRAPEVQLKA TKAEQAEGME FGFKMPKMTM PKLGRAESPS RGKPGEAGAE VSGKLVTLPC LQPEVDGEAH VGVPSLTLPS VELDL Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Specifications

• Antigen: PRX
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRX
• Gene Alias: CMT4F; KIAA1620; L-Periaxin; periaxin; PRX
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57716
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BXM0
• Gene Symbols: PRX
• Immunogen: Recombinant protein corresponding to Human PRX. Recombinant protein control fragment (Product #RP-100995).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG