Invitrogen™ PRP8 Recombinant Rabbit Monoclonal Antibody (4I1Q8)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA538118

Product Code. 17246993

Description

Positive Samples: HeLa, 293T, Jurkat, Mouse brain, Mouse spleen Immunogen sequence: MADNPSWDGE KTIIITCSFT PGSCTLTAYK LTPSGYEWGR QNTDKGNNPK GYLPSHYERV QMLLSDRFLG FFMVPAQSSW NYNFMGVRHD PNMKYELQLA NPKEFYHEVH RPSHFLNFAL LQEGEVYSAD REDLYA.

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

Specifications

• Antigen: PRP8
• Classification: Recombinant Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6P2Q9, Q99PV0
• Gene Symbols: Prpf8
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2200-2335 of human PRPF8 (Q6P2Q9).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 4I1Q8
• Conjugate: Unconjugated
• Gene: Prpf8
• Gene Alias: 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; AU019467; D11Bwg0410e; DBF3/PRP8; H PRPC8; HPRP8; id:ibd1257; ik:tdsubc_2a9; im:7141966; p220; precursor mRNA processing protein; pre-mRNA processing factor 8; pre-mRNA-processing-splicing factor 8; Prp8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; prpf8; RP13; Sfprp8l; SNRNP220; spl; Splicing factor Prp8; tdsubc_2a9; U5 snRNP-specific protein; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p; wu:fb37c02; wu:fb73e06; xx:tdsubc_2a9; zgc:56504
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10594, 192159, 287530
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid