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Invitrogen™ PRP8 Polyclonal Antibody
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Product Code. 16589331
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Quantity:
100 μL
Unit Size:
100µL
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16589331 100 μL 100µL
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Product Code. 16589331 Supplier Invitrogen™ Supplier No. PA596497

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGVFPYRGP GNPVPGPLAP LPDYMSEEKL QEKARKWQQL QAKRYAEKRK FGFVDAQKED MPPEHVRKII RDHGDMTNRK FRHDKRVYLG ALKYMPHAVL; Positive Samples: HeLa, Jurkat; Cellular Location: Nucleus speckle.

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRP8
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.99 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Prpf8
Gene Accession No. Q6P2Q9, Q99PV0
Gene Alias 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; AU019467; D11Bwg0410e; DBF3/PRP8; H PRPC8; HPRP8; id:ibd1257; ik:tdsubc_2a9; im:7141966; p220; precursor mRNA processing protein; pre-mRNA processing factor 8; pre-mRNA-processing-splicing factor 8; Prp8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; prpf8; RP13; Sfprp8l; SNRNP220; spl; Splicing factor Prp8; tdsubc_2a9; U5 snRNP-specific protein; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p; wu:fb37c02; wu:fb73e06; xx:tdsubc_2a9; zgc:56504
Gene Symbols Prpf8
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRPF8 (NP_0064363).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10594, 192159, 287530
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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