Invitrogen™ Prothrombin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA586933

Product Code. 16373795

Description

Purity is > 95% by SDS-PAGE.

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Specifications

• Antigen: Prothrombin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F2
• Gene Alias: Activation peptide fragment 1; Activation peptide fragment 2; bovine prothrombin protein; Cf2; Cf-2; coagulation factor 2; coagulation factor II; coagulation factor II (thrombin); coagulation factor II [thrombin]; coagulation factor II, thrombin; F2; FII; kringle-2 domain; fragment-2; prepro-coagulation factor II; preprothrombin; prothrombin; prothrombin B-chain; prothrombin precursor; PT; RPRGL2; serine protease; THPH1; THROMBIN; Thrombin heavy chain; Thrombin light chain
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14061, 2147, 29251
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00734, P18292, P19221
• Gene Symbols: F2
• Immunogen: Synthetic peptide, corresponding to amino acids 430-480 of Human Prothrombin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG