ProSAPiP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 24936-1-AP-20UL

Product Code. 16863455

Description

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through a PDZ domain in ProSAP2/Shank3 and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ′Fezzins′. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Specifications

• Antigen: ProSAPiP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LZTS3
• Gene Alias: KIAA0552, ProSAP interacting protein 1, ProSAPiP1, ProSAPiP1 protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 241638, 9762
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: A2AHG0, O60299
• Gene Symbols: LZTS3
• Immunogen: ProSAPiP1 Fusion Protein Ag20765
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG