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Invitrogen™ Prosapip1 Polyclonal Antibody

Product Code. 12838992
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Quantity:
100 μg
Unit Size:
100µg
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12838992 100 μg 100µg
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Product Code. 12838992 Supplier Invitrogen™ Supplier No. PA520816

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Description

Rabbit Polyclonal Antibody

A suggested positive control is SK-N-SH cell lysate. PA5-20816 can be used with blocking peptide PEP-0930.

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through a PDZ domain in ProSAP2/Shank3 and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prosapip1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Lzts3
Gene Accession No. A2AHG0, O60299, Q8K1Q4
Gene Alias KIAA0552; Leucine zipper putative tumor suppressor 3; leucine zipper tumor suppressor family member 3; leucine zipper, putative tumor suppressor family member 3; LZTS3; proline rich synapse associated protein interacting protein 1; proline rich synapse associated protein interacting protein 1 (Prosapip1); ProSAP/Shank-interacting protein 1; proSAP-interacting protein 1; PROSAPIP1
Gene Symbols Lzts3
Host Species Rabbit
Immunogen A 16 amino acid peptide from near the carboxy terminus of human Prosapip1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 241638, 280670, 9762
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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