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Invitrogen™ CXCR2 Polyclonal Antibody
Description
Predicted molecular weight of 55 kDa.
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Specifications
Specifications
| Antigen | CXCR2 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Tris glycine with 0.5% BSA, 30% glycerol and 0.02% sodium azide; pH 7.4-7.9 |
| Gene | CXCR2 |
| Gene Accession No. | P25025, P35343, P35407 |
| Gene Alias | C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD128; CD182; CD182 antigen; CDw128; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; chemokine (C-X-C) receptor 2; Cmkar2; CXC; C-X-C chemokine receptor type 2; CXC motif chemokine; C-X-C motif chemokine receptor 2; Cxcr2; CXC-R2; CXCR-2; CXCR2 gene for IL8 receptor type B; Gpcr16; GRO/MGSA receptor; high affinity interleukin-8 receptor B; IL-8 receptor alpha chain; Il-8 receptor b; IL-8 receptor beta; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; Il8rb; IL-8rb; IL-8Rh; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin 8 receptor, beta; interleukin-8 receptor type B; mIL-8RH |
| Gene Symbols | CXCR2 |
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