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Invitrogen™ Prohibitin Monoclonal Antibody (5H7)

Product Code. 12817922
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12817922 100 μL 100µL
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Product Code. 12817922 Supplier Invitrogen™ Supplier No. MA515899

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Description

Mouse Monoclonal Antibody

MA5-15899 targets PHB in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15899 immunogen is purified recombinant fragment of human PHB expressed in E. Coli. . MA5-15899 detects PHB which has a predicted molecular weight of approximately 30kDa.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prohibitin
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5H7
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene PHB
Gene Accession No. P35232, P67778, P67779
Gene Alias BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
Gene Symbols PHB
Host Species Mouse
Immunogen Purified recombinant fragment of human PHB expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18673, 25344, 5245
Target Species Human, Mouse, Rat, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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