Progesterone Receptor Ab-2, Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ Progesterone Receptor Ab-2, Mouse Monoclonal Antibody.

Brand:  Epredia MS-192-P1ABX

Product Code. 12650477

Description

Human PgR exists in two forms: 116kDa (B-form) and 81kDa (A-form). It acts as ligand activated transcription factor to regulate expression of the target genes. Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities.

Host Species: Mouse

Clone: hPRa 2

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Horse, Rabbit, and Chicken. Does not react with monkey. Others not known.

Epitope: N-terminal half of human progesterone

Immunogen: PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice

Molecular Weight: 116kDa (triplet, B-form)

Positive Control: T47D cells or Breast CA

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native and denatured)
• Sedimentation in Sucrose Gradient

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Progesterone Receptor Ab-2
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Cancer and Tumor Biology
• Target Species: Bovine, Chicken, Equine, Human, Rabbit
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: hPRa 2
• Conjugate: Unconjugated
• Immunogen: PgR from a human endometrial carcinoma (EnCa 101) grown in athymic mice
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated