Invitrogen™ PRMT5 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C136)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA548331

Product Code. 17901551

Description

Specificity: This antibody recognizes PRMT5 (Protein arginine N-methyltransferase 5). It binds to a folded domain, amino acids 269-637. PRMT5 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.

PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.

Specifications

• Antigen: PRMT5 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: O14744
• Gene Symbols: PRMT5
• Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing PRMT5 protein under non-denaturing conditions.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ChIP Assay, ELISA, Flow Cytometry, Immunoprecipitation, Immunocytochemistry
• Clone: RAB-C136
• Conjugate: Unconjugated
• Gene: PRMT5
• Gene Alias: 72 kDa ICln-binding protein; EC 2.1.1.125; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; hypothetical protein; I79_013398; IBP72; Jak-binding protein 1; JBP1; PRMT5; protein arginine methyltransferase 5; protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; protein arginine N-methyltransferase 5-like; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog; SKB1Hs
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10419
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid