PRMT4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA517304

Product Code. 11576121

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other PRMT proteins.

Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

Specifications

• Antigen: PRMT4
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
• Gene Accession No.: Q4AE70, Q86X55, Q9WVG6
• Gene Symbols: Carm1
• Immunogen: Synthetic peptide corresponding to the carboxy terminus of the human PRMT4/CARM1 protein
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: Carm1
• Gene Alias: Carm1; coactivator associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; histone-arginine methyltransferase CARM1; PRMT4; protein arginine methyltransferase; protein arginine N-methyltransferase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10498, 363026, 59035
• Content And Storage: -20°C
• Form: Liquid