Invitrogen™ PRKY Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536511

Product Code. 15543901

Description

This antibody detects endogenous protein at a molecular weight of 32 kDa. Purity is >95% by SDS-PAGE.

A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. PRKY (protein kinase, Y-linked) and PRKX (protein kinase, X-linked) are members of the Ser/Thr protein kinase family, both of which belong to the subfamily of cAMP-dependent kinases. Encoded by a gene that is located near the pseudoautosomal region on chromosome Y, PRKY contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Functioning in a similar manner to PRXY, PRKX contains one protein kinase domain and is essential for macrophage differentiation and renal epithelial cell migration. Defects in the genes encoding PRKY and PRXX are associated with sex reversal disorder, namely XX in males and XY in females.

Specifications

• Antigen: PRKY
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRKY
• Gene Alias: PRKXP3; PRKY; PRKYP; protein kinase, Y-linked, pseudogene
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5616
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43930
• Gene Symbols: PRKY
• Immunogen: Synthetic peptide corresponding to amino acids 61-110 of human PRKY.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG