Invitrogen™ PREX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5117672

Product Code. 17210174

Description

This antibody has been tested in direct-ELISA.

Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.

Specifications

• Antigen: PREX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PREX2
• Gene Alias: 6230420N16Rik; AI316880; AI553603; C030045D06Rik; D430013K02; DEP domain containing 2; DEP domain-containing protein 2; DEP.2; Depdc2; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; PPP1R129; Prex2; P-Rex2; protein phosphatase 1, regulatory subunit 129; ptdIns(3,4,5)-dependent Rac exchanger 2; si:ch211-278g15.1
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 109294, 80243
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q3LAC4, Q70Z35
• Gene Symbols: PREX2
• Immunogen: Recombinant Human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592aa).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG