Invitrogen™ PREP Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547611

Product Code. 15558102

Description

In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant mouse PREP is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Specifications

• Antigen: PREP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PREP
• Gene Alias: AI047692; AI450383; D10Wsu136e; dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250; PEP; Pop; post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250; Prep; prep {ECO:0000312; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250; prolyl oligopeptidase; RGD:620841}; rPop; UniProtKB:P23687}
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5550
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P48147
• Gene Symbols: PREP
• Immunogen: Sf 21-derived recombinant human PREP Leu2-Pro710.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG