Invitrogen™ PRELP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5144877

Product Code. 18065851

Description

Immunogen sequence: GLRWINLDNN RIRKIDQRVL EKLPG Antigen sequence identity: Mouse 84%; Rat 96%.

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Specifications

• Antigen: PRELP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRELP
• Gene Alias: 55 kDa leucine-rich repeat protein of articular cartilage; 7330409J17Rik; MST161; MSTP161; PRELP; Prolargin; prolargin proteoglycan; proline and arginine rich end leucine rich repeat protein; proline arginine-rich end leucine-rich repeat; proline/arginine-rich end leucine-rich repeat protein; proline-arginine-rich end leucine-rich repeat protein; SLRR2A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5549
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P51888
• Gene Symbols: PRELP
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 127-151. Recombinant protein control fragment (Product #RP-109763).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid