Invitrogen™ PRDX6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA580935

Product Code. 16398004

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Peroxiredoxin 6/PRDX6.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRDX6
• Gene Alias: 1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 1-cysPrx; 24 kDa protein; 9430088D19Rik; AA690119; Acidic calcium-independent phospholipase A2; aiPLA2; Antioxidant protein 2; Aop2; Brp-12; CP-3; epididymis secretory sperm binding protein Li 128m; GPx; HEL-S-128m; KIAA0106; Liver 2D page spot 40; Ltw4; Ltw-4; Lvtw-4; MGC46173; MSP23; NKEFA; Non-selenium glutathione peroxidase; NSGPx; ORF06; p29; PAG; PAGA; PAGB; peroxiredoxin 6; peroxiredoxin-6; Prdx5; Prdx6; PRX; Prx6; Red blood cells page spot 12; thiol-specific antioxidant protein; Tsa
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9588
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P30041
• Gene Symbols: PRDX6
• Immunogen: Recombinant Human Peroxiredoxin 6/PRDX6 protein (Met1-Pro224).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG