Invitrogen™ PRDX5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576908

Product Code. 15933425

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRDX5
• Gene Alias: ACR1; Alu corepressor 1; Alu co-repressor 1; Antioxidant enzyme B166; AOEB166; AOPP; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 2D-0014IV; liver tissue 2D-page spot 71B; peroxiredoxin 5; peroxiredoxin 6; peroxiredoxin V; Peroxiredoxin-5, mitochondrial; peroxisomal antioxidant enzyme; peroxisomal membrane protein 20; PLP; Pmp20; PRDX5; Prdx6; Prx5; PrxV; prx-V; SBBI10; Thioredoxin peroxidase PMP20; thioredoxin reductase; TPx type VI
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113898, 25824, 54683
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P30044, P99029, Q9R063
• Gene Symbols: PRDX5
• Immunogen: Recombinant full length Human PRDX5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG