Invitrogen™ PRDX5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA579864

Product Code. 15985425

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: A549 whole cell, Rat Brain Tissue, Mouse Brain Tissue. IHC: Human Lung Cancer Tissue, Rat Intestine Tissue, Mouse Intestine Tissue. ICC/IF: HELA cell, SMMC cell. Flow: A549 cell.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.

Specifications

• Antigen: PRDX5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRDX5
• Gene Alias: ACR1; Alu corepressor 1; Alu co-repressor 1; Antioxidant enzyme B166; AOEB166; AOPP; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 2D-0014IV; liver tissue 2D-page spot 71B; peroxiredoxin 5; peroxiredoxin 6; peroxiredoxin V; Peroxiredoxin-5, mitochondrial; peroxisomal antioxidant enzyme; peroxisomal membrane protein 20; PLP; Pmp20; PRDX5; Prdx6; Prx5; PrxV; prx-V; SBBI10; Thioredoxin peroxidase PMP20; thioredoxin reductase; TPx type VI
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113898, 25824, 54683
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P30044, P99029, Q9R063
• Gene Symbols: PRDX5
• Immunogen: E.coli-derived human Peroxiredoxin 5 recombinant protein (Position: E66-D198).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG