Invitrogen™ PRAME Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5139892

Product Code. 17834410

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: VLDLRKNSHQ DFWTVWSGNR ASLYSFPEPE AAQPMTKKRK VDGLSTEAEQ PFIPVEVLVD LFLKEGACDE LFSYLIEKVK RKKNVLRLCC KKLKIFAMPM QDIKMILKMV QLDSIEDLEV TCTWKLPTL Highest antigen sequence indentity to the following orthologs: Mouse - 40%, Rat - 40%.

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.

Specifications

• Antigen: PRAME
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRAME
• Gene Alias: 4930534P07Rik; cancer/testis antigen 130; CT130; MAPE; melanoma antigen preferentially expressed in tumors; OIP4; OIP-4; Opa-interacting protein 4; Opa-interacting protein OIP4; PRAME; preferentially expressed antigen in melanoma; preferentially expressed antigen of melanoma
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23532
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P78395
• Gene Symbols: PRAME
• Immunogen: Recombinant protein corresponding to Human PRAME. Recombinant protein control fragment (Product #RP-109161).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG