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Invitrogen™ PRAK Polyclonal Antibody
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Product Code. 13412737
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
13412737 100 μL 100µL
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Product Code. 13412737 Supplier Invitrogen™ Supplier No. PA528616

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2. Predicted reactivity: Mouse (98%), Rat (96%), Zebrafish (92%), Pig (98%), Chicken (97%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRAK
Applications Western Blot
Classification Polyclonal
Concentration 0.62 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene MAPKAPK5
Gene Accession No. Q8IW41
Gene Alias MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Gene Symbols MAPKAPK5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PRAK. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8550
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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