PPP2R5D Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA528445

Product Code. 13462557

Description

Recommended positive controls: HeLa, A549, IMR32, HCT116, PPP2R5D shRNA-transfected HeLa. Predicted reactivity: Mouse (100%), Pig (100%), Rabbit (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family. Localized to the nucleus, ZNF265 functions as a splicing factor that is responsible for alternatively splicing Tra-2 beta (transformer-2 beta) transcripts and is thought to interfere with constitutive 5'-splice selection. ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

Specifications

• Antigen: PPP2R5D
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP2R5D
• Gene Alias: B56D; B'delta; MGC2134; MGC8949; MRD35; PP2A B subunit isoform B56-delta; PP2A B subunit isoform B'-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta; PP2A, B subunit, B' delta isoform; PP2A, B subunit, B56 delta isoform; PP2A, B subunit, PR61 delta isoform; PP2A, B subunit, R5 delta isoform; PP2CB; Ppp2r5d; protein phosphatase 2 regulatory subunit B'delta; protein phosphatase 2, regulatory subunit B (B56), delta isoform; protein phosphatase 2, regulatory subunit B', delta; protein phosphatase 2, regulatory subunit B', delta isoform; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; TEG-271; testis expressed gene 271; Tex271
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5528
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14738
• Gene Symbols: PPP2R5D
• Immunogen: Synthetic peptide corresponding to a region within amino acids 539 and 602 of Human PPP2R5D
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG