Invitrogen™ PPM1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582557

Product Code. 16399514

Description

Immunogen sequence: KRNVIEAVYS RLNPHRESDG ASDEAEESGS QGKLVEALRQ MRINHRGNYR QLLEEMLTSY RLAKVEGEES PAEPAATATS SNSDAGNPVT MQESHTESES GLAEL Highest antigen sequence indentity to the following orthologs: Mouse - 80%, Rat - 85%.

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Specifications

• Antigen: PPM1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPM1B
• Gene Alias: EGK_05287; Pp2c2; PP2CB; PP2CBETA; PP2C-beta; PP2C-beta-X; PPC2BETAX; PPM1B; Pppm1b; Protein phosphatase 1B; protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform; protein phosphatase 1B, magnesium dependent, beta isoform; protein phosphatase 2C isoform beta; protein phosphatase 2C-like protein; Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform; Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform; protein phosphatase, Mg2+/Mn2+ dependent 1B; protein phosphatase, Mg2+/Mn2+ dependent, 1B; Ser/Thr protein phosphatase type 2C beta 2 isoform
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5495
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75688
• Gene Symbols: PPM1B
• Immunogen: Recombinant protein corresponding to Human PPM1B. Recombinant protein control fragment (Product #RP-91561).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG