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Invitrogen™ PPAPDC3 Polyclonal Antibody

Product Code. 12859012
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12859012 100 μg 100µg
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Product Code. 12859012 Supplier Invitrogen™ Supplier No. PA520866

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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse heart tissue lysate. PA5-20866 can be used with blocking peptide PEP-0980.

PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPAPDC3
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Plpp7
Gene Accession No. Q5FVJ3, Q8NBV4, Q91WB2
Gene Alias C9orf67; D830019K17Rik; Inactive phospholipid phosphatase 7; NET39; Nuclear envelope transmembrane protein 39; nuclear envelope transmembrane protein NET39; phosphatidic acid phosphatase type 2 domain containing 3; phosphatidic acid phosphatase type 2 domain-containing protein 3; phospholipid phosphatase 7 (inactive); PLPP7; Ppapdc3; probable lipid phosphate phosphatase PPAPDC3; RGD1305821; RP11-643E14.1
Gene Symbols Plpp7
Host Species Rabbit
Immunogen A 19 amino acid peptide from near the amino of terminus human PPAPDC3.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 227721, 296635, 84814
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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