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Invitrogen™ PPAPDC1A Polyclonal Antibody

Product Code. 12829012 Shop All Thermo Scientific Products
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Quantity:
100 μg
Unit Size:
100µg
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12829012 100 μg 100µg
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Product Code. 12829012 Supplier Invitrogen™ Supplier No. PA520864

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-20864 can be used with blocking peptide PEP-0978.

Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPAPDC1A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene PLPP4
Gene Accession No. Q0VBU9, Q5VZY2
Gene Alias C030048B12Rik; diacylglycerol pyrophosphate like 2; diacylglycerol pyrophosphate phosphatase-like 2; DPPL2; Gm1090; phosphatidate phosphatase PPAPDC1A; phosphatidic acid phosphatase type 2 domain containing 1A; phosphatidic acid phosphatase type 2 domain-containing protein 1A; Phospholipid phosphatase 4; PLPP4; PPAPDC1; Ppapdc1a; RGD1306289; RP11-257O17.1
Gene Symbols PLPP4
Host Species Rabbit
Immunogen A 14 amino acid peptide near the carboxy terminus of human PPAPDC1A.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 196051, 309014, 381925
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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