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Eurofins DiscoverX PP5 Protein, Active
Description
PPS (Protein Phosphatase 5 Catalytic Subunit) is a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Diseases associated with PP5 include Microcephaly, Seizures, and Developmental Delay and Breast Cancer. Among its related pathways are DNA Damage and Homology Directed Repair.
GenBank NM_006247
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 83.8 kDa |
| Quantity | 250 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal GST |
| Expression System | Recombinant enzyme expressed in E. coli cells |
| Protein Form | Full-length |
| Purity or Quality Grade | ≥69% |
| Protein | PP5, active |
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