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Ponesimod, MedChemExpress

Product Code. 16440407
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Product Code. 16440407

Brand: Medchem Express HY10569

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Beskrivelse

MedChemExpress Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation.

Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation.

Tekniske data

Chemical Name or Material Ponesimod
CAS 854107-55-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C23H25ClN2O4S
Quantity 50 mg
Synonym ACT-128800
Solubility Information DMSO : ≥ 100 mg/mL (216.93 mM)
SMILES O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[C@H](O)CO)C(Cl)=C3)=N/CCC
Molecular Weight (g/mol) 460.97
Formula Weight 460.97
Percent Purity 98.25%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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