Invitrogen™ PON2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115781

Product Code. 17238563

Description

Antibody detects endogenous levels of total PON2.

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: PON2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PON2
• Gene Alias: 6330405I24Rik; A esterase 2; A-esterase 2; AI481612; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 296851, 330260, 5445
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q15165, Q62086, Q6AXM8
• Gene Symbols: PON2
• Immunogen: A synthesized peptide derived from human PON2(Accession Q15165), corresponding to amino acid residues K249-P299.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG