Invitrogen™ Polysialic acid Chimeric Recombinant Rabbit Monoclonal Antibody (735)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA547855

Product Code. 17991151

Description

Specificity: Recognises Polysialic acid (PSA), a carbohydrate polymer attached to the neural cell adhesion molecule (NCAM), which shares molecular epitopes with homopolymers of alpha-2,8-linked sialic acid of Escherichia coli K1.

Polysialic acid is a glycan polymer composed of repeating units of the monosaccharide sialic acid. It consists of a linear chain of alpha-2,8-linked sialic acid residues that can extend up to 200 units in length. This negatively charged molecule is commonly present in the cell membranes of various organisms, including bacteria and animals, and plays a crucial role in regulating cell adhesion, migration, and neural development. Polysialic acid is also being explored for its potential therapeutic applications in the treatment of certain cancers and neurological disorders.

Specifications

• Antigen: Polysialic acid Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG κ

• Applications: Flow Cytometry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Clone: 735
• Conjugate: Unconjugated
• Gene Alias: polySia; PSA
• Immunogen: Homopolymers of alpha-2,8-linked sialic acid of Escherichia coli K1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid