Invitrogen™ POLR3K Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5103798

Product Code. 16690245

Description

Antibody detects endogenous levels of total RPC10.

Eukaryotes produce 3 distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. POLR3K, also known as DNA-directed RNA polymerase III subunit RPC11, is a 108 amino acid nuclear protein that is one of the seventeen subunits that comprise Pol III. Specifically, POLR3K is a DNA-dependent RNA polymerase that uses the four ribonucleoside triphosphates to catalyze the transcription of DNA to RNA. The gene encoding POLR3K maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs and is associated with a variety of genetic disorders.

Specifications

• Antigen: POLR3K
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR3K
• Gene Alias: 12.3kDa; 1500004O14Rik; AI196849; AU014893; C11; C11-RNP3; DNA-directed RNA polymerase III subunit K; DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerases III 12.5 kDa polypeptide; estrous-specific protein, 250 kDa; hRPC11; HsC11p; My010; POLR3K; polymerase (RNA) III (DNA directed) polypeptide K; polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa; polymerase (RNA) III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C10; RNA polymerase III subunit C11; RNA polymerase III subunit CII; RNA polymerase III subunit K; RPC10; RPC11; RPC12.5
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 366277, 51728, 67005
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9CQZ7, Q9Y2Y1
• Gene Symbols: POLR3K
• Immunogen: A synthesized peptide derived from human POLR3K(Accession Q9Y2Y1), corresponding to amino acid residues G17-E67.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG