Invitrogen™ POLR3K Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552220

Product Code. 15760171

Description

Immunogen sequence: PGCGNGLIVE EGQRCHRFAC NTCPYVHNIT RKVTNRKYPK LKEVDDVLGG AAAWENVDST AESCPKCEHP RAYFMQLQTR SADEPMTTFY KCCNAQCGHR WRD Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Eukaryotes produce 3 distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. POLR3K, also known as DNA-directed RNA polymerase III subunit RPC11, is a 108 amino acid nuclear protein that is one of the seventeen subunits that comprise Pol III. Specifically, POLR3K is a DNA-dependent RNA polymerase that uses the four ribonucleoside triphosphates to catalyze the transcription of DNA to RNA. The gene encoding POLR3K maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs and is associated with a variety of genetic disorders.

Specifications

• Antigen: POLR3K
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR3K
• Gene Alias: 12.3kDa; 1500004O14Rik; AI196849; AU014893; C11; C11-RNP3; DNA-directed RNA polymerase III subunit K; DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerases III 12.5 kDa polypeptide; estrous-specific protein, 250 kDa; hRPC11; HsC11p; My010; POLR3K; polymerase (RNA) III (DNA directed) polypeptide K; polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa; polymerase (RNA) III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C10; RNA polymerase III subunit C11; RNA polymerase III subunit CII; RNA polymerase III subunit K; RPC10; RPC11; RPC12.5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51728
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.10 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y2Y1
• Gene Symbols: POLR3K
• Immunogen: Recombinant protein corresponding to Human POLR3K. Recombinant protein control fragment (Product #RP-89380).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG