Invitrogen™ POLR2C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595927

Product Code. 16518771

Description

Immunogen sequence: MPYANQPTVR ITELTDENVK FIIENTDLAV ANSIRRVFIA EVPIIAIDWV QIDANSSVLH DEFIAHRLGL IPLISDDIVD KLQYSRDCTC EEFCPECSVE FTLDVRCNED QTRHVTSRDL ISNSPRVIPV TSRNRDNDPN DYVEQDDILI VKLRKGQELR LRAYAKKGFG KEHAKWNPTA GVAFEYDPDN ALRHTVYPKP EEWPKSEYSE LDEDESQAPY DPNGKPERFY YNVESCGSLR PETIVLSALS GLKKKLSDLQ TQLSHEIQSD VLTIN; Positive Samples: SW620, OVCAR3, Mouse spleen; Cellular Location: Nucleus.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft.

Specifications

• Antigen: POLR2C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2C
• Gene Alias: 33kDa; A-152E5.7; DNA-directed RNA polymerase II 33 kDa polypeptide; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II subunit RPB3; hRPB33; hsRPB3; mRBP31; Polr2c; polymerase (RNA) II (DNA directed) polypeptide C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II subunit C; polymerase II polypeptide C; RNA polymerase II 3; RNA polymerase II subunit 3; RNA polymerase II subunit B3; RNA polymerase II subunit C; RPB3; RPB31; RPB33; Rpo2-3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20021, 5432
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P19387, P97760
• Gene Symbols: POLR2C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human RPB3/POLR2C (NP_1165581).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG