Invitrogen™ POLD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550951

Product Code. 15631194

Description

DNA pol δ3 Polyclonal Antibody detects endogenous levels of DNA pol δ3 protein.

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.

Specifications

• Antigen: POLD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLD3
• Gene Alias: 2410142G14Rik; C85233; DNA pol delta3; DNA polymerase delta 3, accessory subunit; DNA polymerase delta subunit 3; DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68; DNA-directed DNA polymerase delta 3; DNApol delta3; GC12; KIAA0039; P66; P68; Pol delta C subunit (p66); POLD3; polymerase (DNA directed), delta 3; polymerase (DNA) delta 3, accessory subunit; polymerase (DNA-directed), delta 3, accessory subunit; PPP1R128; protein phosphatase 1, regulatory subunit 128
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10714, 293144, 67967
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q15054, Q9EQ28
• Gene Symbols: POLD3
• Immunogen: Synthesized peptide derived from the C-terminal region of human DNA pol delta3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG