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Invitrogen™ POLD3 Polyclonal Antibody
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Product Code. 15731392 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15731392 100 μL 100µL
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Product Code. 15731392 Supplier Invitrogen™ Supplier No. PA563618

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SVTEPKLATP AGLKKSSKKA EPVKVLQKEK KRGKRVALSD DETKETENMR KKRRRIKLPE SDSSEDEVFP DSPGAY Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLD3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLD3
Gene Accession No. Q15054
Gene Alias 2410142G14Rik; C85233; DNA pol delta3; DNA polymerase delta 3, accessory subunit; DNA polymerase delta subunit 3; DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68; DNA-directed DNA polymerase delta 3; DNApol delta3; GC12; KIAA0039; P66; P68; Pol delta C subunit (p66); POLD3; polymerase (DNA directed), delta 3; polymerase (DNA) delta 3, accessory subunit; polymerase (DNA-directed), delta 3, accessory subunit; PPP1R128; protein phosphatase 1, regulatory subunit 128
Gene Symbols POLD3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human POLD3. Recombinant protein control fragment (Product #RP-103343).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10714
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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