Invitrogen™ POLB Recombinant Rabbit Monoclonal Antibody (24GB1475)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30276544	Invitrogen™ MA557383	100 μL
30275124	Invitrogen™ MA557384	20 μL

Description

POLB Recombinant Monoclonal Antibody for Western Blot

DNA polymerase beta comprises an amino-terminal 8- kDa domain and a carboxy-terminal 31- kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase beta, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates beta-pol level. DNA polymerase beta fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.

Specifications

• Antigen: POLB
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse, Rat
• Gene: POLB
• Gene Alias: A430088C08Rik; DNA pol beta; DNA polymerase beta; DNA polymerase beta subunit; DNA-directed DNA polymerase beta; hypothetical protein LOC614688; LOW QUALITY PROTEIN: DNA polymerase beta; MGC125976; POL B; Pol beta; POLB; polb.S; polymerase (DNA directed), beta; polymerase (DNA directed), beta S homeolog; polymerase (DNA) beta; polymerase B; polymerase-beta; wu:fa97a05; XELAEV_18020165mg; zgc:109924
• Gene Symbols: POLB
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: 24GB1475
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P06746, P06766, Q8K409
• Gene ID (Entrez): 18970, 29240, 5423
• Immunogen: A synthesized peptide derived from human DNA polymerase beta (aa 300-335).
• Product Type: Antibody