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Invitrogen™ POFUT1 Polyclonal Antibody

Product Code. 12808762
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Quantity:
100 μg
Unit Size:
100µg
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12808762 100 μg 100µg
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Product Code. 12808762 Supplier Invitrogen™ Supplier No. PA520581

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human heart tissue lysate. PA5-20581 can be used with blocking peptide PEP-0701.

POFUT1, an endoplasmic reticulum-residing member of the glycosyltransferase O-Fuc family, adds O-fucose through an O-glycosidic linkage to conserved serine or threonines in epidermal growth factor-like repeats of several cell surface and secreted proteins. Unlike its homolog POFUT2, POFUT1 can also catalyze the transfer of fucose to thrombospondin type 1 repeats. Many of the substrates of POFUT1 are involved in ligand-induced receptor signaling. One such protein is Notch; mouse ES cells lacking POFUT have normal levels of Notch receptors at the cell surface, but these receptors do not bind Notch ligands or exhibit Notch signaling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POFUT1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene POFUT1
Gene Accession No. Q91ZW2, Q9H488
Gene Alias DDD2; FUT12; GDP-fucose protein O-fucosyltransferase 1; KIAA0180; mKIAA0180; o-fucosyltransferase protein; O-Fuc-T; OFUCT1; O-FucT-1; O-FucT-1a; O-FucT-1b; O-FUT; peptide-O-fucosyltransferase 1; Pofut1; pofut1 {ECO:0000312; protein O-fucosyltransferase 1; protein O-fucosyltransferase 1 isoform 1 precursor; protein O-fucosyltransferase 1a; protein O-fucosyltransferase 1b; protein-O-fucosyltransferase 1; RGD:1303001}; zgc:110472
Gene Symbols POFUT1
Host Species Rabbit
Immunogen A 16 amino acid peptide from near the amino terminus of human POFUT1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140484, 23509
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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