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Podoplanin Rat anti-Human, APC, Clone: NZ-1.3, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-9381-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15538246

  • £84.99 / 25 tests


EU Stock 6
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Disclaimers:

For Research Use Only.


Description

Description

Podoplanin is a 40kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2).

This antibody has been reported to block the interaction between Podoplanin and CLEC-2.
Specifications

Specifications

Podoplanin
NZ-1.3
APC
Conjugated
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.125μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
PDPN
IgG2a
RUO
Primary
Human