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PNU-159682, MedChemExpress

Product Code. 16497138
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Product Code. 16497138

Brand: Medchem Express HY16700

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Description

MedChemExpress PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome drug resistance.

PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome drug resistance.

Specifications

Chemical Name or Material PNU-159682
CAS 202350-68-3
Color Reddish Brown
Purity Grade Notes Research
Molecular Formula C32H35NO13
Quantity 10 mg
Solubility Information DMSO : 100 mg/mL (155.86 mM; Need ultrasonic)
SMILES COC1=C(C(C(C(O)=C([C@@H](O[C@H]2C[C@H]3[C@H](O[C@H]4N3CCO[C@@H]4OC)[C@H](C)O2)C[C@@](C(CO)=O)(O)C5)C5=C6O)=C6C7=O)=O)C7=CC=C1
Molecular Weight (g/mol) 641.62
Formula Weight 641.62
Percent Purity 95.11%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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