Invitrogen™ PNR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534005

Product Code. 15372361

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Hamster, Elephant, Panda, Bovine, Bat, Horse, Pig (100%) Marmoset (95%).

NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Specifications

• Antigen: PNR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NR2E3
• Gene Alias: A930035N01Rik; ESCS; MGC138414; MGC138416; Nr2e3; Nuclear receptor subfamily 2 group E member 3; nuclear receptor subfamily 2, group E, member 3; photoreceptor-specific nuclear receptor; PNR; rd7; retinal degeneration 7; Retina-specific nuclear receptor; Rnr; RP11-295F4.5; RP37; taR-5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10002, 100063879, 100752298, 102159757, 23958, 281944
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9QXZ7, Q9TTF0, Q9Y5X4
• Gene Symbols: NR2E3
• Immunogen: Synthetic 19 amino acid peptide from ligand-binding domain of human NR2E3.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Bovine, Hamster, Pig, Horse, Bat
• Product Type: Antibody
• Isotype: IgG