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PND-1186, MedChemExpress

Product Code. 16488547
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Product Code. 16488547 Supplier Medchem Express Supplier No. HY13917
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Estimated Shipment: 03-08-2026
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Description

MedChemExpress PND-1186 (VS-4718) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis.

PND-1186 (VS-4718) is a potent, highly-specific and reversible inhibitor of FAK with an IC50 of 1.5 nM. PND-1186 selectively promotes tumor cell apoptosis.

Specifications

Chemical Name or Material PND-1186
CAS 1061353-68-1
Color White
Purity Grade Notes Research
Molecular Formula C25H26F3N5O3
Quantity 5 mg
Synonym VS-4718 SR-2516
Solubility Information DMSO : ≥ 34 mg/mL (67.80 mM)
SMILES O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2C(F)(F)F
Molecular Weight (g/mol) 501.5
Formula Weight 501.5
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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