Invitrogen™ PMS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102597

Product Code. 16639064

Description

Antibody detects endogenous levels of total PMS1.

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

Specifications

• Antigen: PMS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PMS1
• Gene Alias: DNA mismatch repair protein PMS1; HNPCC3; hPMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; MLH2; PMS1; PMS1 homolog 1, mismatch repair system component; PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; PMSL1; postmeiotic segregation increased 1 (S. cerevisiae); rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 494322, 5378
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P54277
• Gene Symbols: PMS1
• Immunogen: A synthesized peptide derived from human PMS1(Accession P54277), corresponding to amino acid residues N443-I493.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG