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PLX51107, MedChemExpress

Product Code. 16410767
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
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Product Code. 16410767

Brand: Medchem Express HY111422

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Description

MedChemExpress PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively; PLX51107 also interacts with the bromodomains of CBP and EP300 (Kd, in the 100 nM range).

PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively

Specifications

Chemical Name or Material PLX51107
CAS 1627929-55-8
Color White
Purity Grade Notes Research
Molecular Formula C26H22N4O3
Quantity 50 mg
Solubility Information DMSO : 75 mg/mL (171.05 mM; Need ultrasonic)
SMILES C[C@@H](C1=NC=CC=C1)N2C=C(C3=CC=C(C(O)=O)C=C3)C4=NC=C(C5=C(C)ON=C5C)C=C42
Molecular Weight (g/mol) 438.48
Formula Weight 438.48
Percent Purity 99.65%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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