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STEMCELL Technologies PluriSIn-1

Product Code. 17140132
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50 mg
Unit Size:
50mg
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Product Code. 17140132 Supplier STEMCELL Technologies Supplier No. 72824

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Description

Oleic acid biosynthesis pathway inhibitor; Inhibits Stearoyl-CoA Desaturase (SCD1)

  • PluriSIn-1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (Ben-David et al.)
  • Selectively eliminates undifferentiated human embryonic stem (ES) and induced pluripotent stem (iPS) cells while sparing differentiated cells, and prevents teratoma formation in transplanted mice (Ben-David et al.)
  • Induces apoptosis of Nanog-positive iPS cells in vitro, while leaving iPS cell-derived cardiomyocytes unaffected (Zhang et al.)

Specifications

CAS 91396-88-2
Synonym N’-phenyl-hydrazine-Isonicotinic acid; NSC 14613
Quantity 50 mg
Molecular Formula C12H11N3O
Purity ≥95%
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