Invitrogen™ PLS3 Monoclonal Antibody (C4), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17920753	Invitrogen™ MA551120	20 μL
17979462	Invitrogen™ MA551119	200 μL

Description

Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Specifications

• Antigen: PLS3
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: AI115446; AL024105; BMND18; LOW QUALITY PROTEIN: plastin-3; MGC128570 protein; plastin 3; plastin 3 (T isoform); plastin 3 (T-isoform); plastin 3, T; plastin-3; PLS3; T fimbrin; T plastin; T-fimbrin; T-plastin
• Gene Symbols: PLS3
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: PLS3

• Clone: C4
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human, Pig, Rat
• Gene Accession No.: P13797, Q63598
• Gene ID (Entrez): 100158187, 5358, 81748
• Immunogen: Recombinant Human PLS3 protein, Ala379-Val630 (Accession #P13797).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.